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J Sex Med ; 9: Methods This is a systematic literature review of HT safety for transgender adults. Conclusions Many transgender individuals seek cross-sex hormone therapy for treatment of gender dysphoria. The effects of the pellets may last up to 6 months, but most patients require re-implantation every 3 to 4 months. Follicle-stimulating hormone Human chorionic gonadotropin Luteinizing hormone Menotropin Urofollitropin. Estrogens are the mainstay therapy for trans female patients. Estrogen is the predominant sex hormone that slows bone loss, even in men. It may be that a transgender individual who feels male or female has a brain structure similar to those of other males or females, respectively, Olson said.
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